The Cadillac Sixteen is unlocked when the player completes the career in the game, also known as 100% completion, (77% in Remix), or it can be purchased for $250,000 if sold.
Handling is on the muscle car side but a lot worse as the steering lacks response compared to classic muscle cars which have quick response. Acceleration is on the lazy side as it is unable to outrun a Mitsubishi Eclipse. Once fully upgraded, though, it is competitive against a lot of D-class cars and some C-class cars, but due to its extremely heavy mass, soft suspension, poor handling and acceleration, it is unable to stand a chance against B-class and A-class cars.
The car can plow through traffic very easily, especially when using Agro, and does not damage easily due to its very heavy mass. Making a quick getaway in race starts is very tricky, even with NOS.